The smart Trick of ceesdekker That Nobody is Discussing

The smart Trick of ceesdekker That Nobody is Discussing

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2009, discovery of a completely new phenotype for bacteria in narrow nanofluidic slits; and initially detection of area protein buildings together DNA working with good-point out nanopores

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2007, initially real-time detection of strand exchange in homologous recombination by RecA; discovery of the small persistence length of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes

We build stage-of-treatment diagnostics take a look at of neglected tropical ailments inside resource-limited configurations, determined by Crspr/Cas9 detecting of pathogen’s DNA in entire body fluids.

The coiled-coil with the human Rad50 DNA fix protein contains precise segments of improved flexibility

Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. Not long ago his investigation has focused on researching cell division with bacteria on chip, while his best curiosity is in cees dekker the way of acknowledging synthetic cells.

Atomic drive microscopy exhibits that vaccinia topoisomerase IB generates filaments on DNA in the cooperative manner

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Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding because the stage-producing procedure

‘The concept There's this type of issue to be a beginning, a large bang, is previously a fascinating signpost to look at that there was a creator. But more typically, and on The idea of pure rationality, I also arrive at a Christian interpretation of fact. An atheistic worldview is often a naturalistic worldview: essentially, there are actually only atoms and natural forces that we are able to measure.

2006, initially demonstration of molecular sorting in a lab on the chip employing biomotors; discovery of nanobubbles in solid-state nanopores; and 1st estimate of electrokinetic Electricity conversion in a nanofluidic channel

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes

Reliable-condition nanopores have verified to get a amazingly functional probe for one-molecule Investigation of DNA. I'll describe a few of our latest findings – particularly DNA knots – in addition to our efforts to expand the abilities of good-point out nanopores even even further, from the course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.